A new research study explored the impact of the main green tea compound, EGCG, on the interactions between estradiol, nicotine, and breast cancer cell growth. For this study, the investigators cultured breast cancer cells and tested them using a variety of analytical techniques. The breast cancer researchers reported that:
- Both nicotine and estradiol approximately doubled the activity of the nAChR receptor pathway.
- Breast cancer cell growth was stimulated by both nicotine and estradiol.
- Treatment with green tea EGCG suppressed the presence of the nAChR nicotine receptors in breast cancer cells, resulting in the suppression of breast cancer cell growth.
- Green tea EGCG also inhibited the binding of nicotine to the nicotine receptor.
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